| Dataset | RNR_GSEA_DESEQ2_FC |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_pos |
| GeneSet | KEGG_NEUROTROPHIN_SIGNALING_PATHWAY |
| Enrichment Score (ES) | 0.12605949 |
| Normalized Enrichment Score (NES) | 1.6102055 |
| Nominal p-value | 0.04192872 |
| FDR q-value | 0.22866435 |
| FWER p-Value | 0.981 |

| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | IRS4 | 81 | 2.329 | 0.0036 | Yes | ||
| 2 | BDNF | 380 | 1.046 | -0.0045 | Yes | ||
| 3 | CALML3 | 521 | 0.869 | -0.0040 | Yes | ||
| 4 | IRS2 | 976 | 0.534 | -0.0206 | Yes | ||
| 5 | BCL2 | 1364 | 0.382 | -0.0335 | Yes | ||
| 6 | FASLG | 1759 | 0.300 | -0.0468 | Yes | ||
| 7 | KIDINS220 | 1763 | 0.300 | -0.0389 | Yes | ||
| 8 | PIK3R1 | 1822 | 0.289 | -0.0341 | Yes | ||
| 9 | CAMK4 | 1914 | 0.273 | -0.0310 | Yes | ||
| 10 | NFKBIA | 1927 | 0.270 | -0.0236 | Yes | ||
| 11 | GAB1 | 2041 | 0.257 | -0.0217 | Yes | ||
| 12 | AKT3 | 2072 | 0.254 | -0.0154 | Yes | ||
| 13 | IRAK3 | 2228 | 0.236 | -0.0157 | Yes | ||
| 14 | FOXO3 | 2405 | 0.218 | -0.0173 | Yes | ||
| 15 | MAP3K3 | 2418 | 0.216 | -0.0099 | Yes | ||
| 16 | TRAF6 | 2441 | 0.214 | -0.0031 | Yes | ||
| 17 | SOS2 | 2763 | 0.188 | -0.0124 | Yes | ||
| 18 | IRS1 | 2893 | 0.179 | -0.0114 | Yes | ||
| 19 | YWHAQ | 3038 | 0.170 | -0.0112 | Yes | ||
| 20 | PIK3CA | 3103 | 0.167 | -0.0066 | Yes | ||
| 21 | PTPN11 | 3250 | 0.157 | -0.0065 | Yes | ||
| 22 | CAMK2D | 3572 | 0.142 | -0.0159 | Yes | ||
| 23 | PIK3R3 | 3580 | 0.141 | -0.0083 | Yes | ||
| 24 | SHC4 | 3668 | 0.137 | -0.0050 | Yes | ||
| 25 | RPS6KA2 | 3812 | 0.130 | -0.0047 | Yes | ||
| 26 | BRAF | 3837 | 0.129 | 0.0020 | Yes | ||
| 27 | GSK3B | 3855 | 0.128 | 0.0091 | Yes | ||
| 28 | PIK3CG | 3956 | 0.124 | 0.0117 | Yes | ||
| 29 | CRK | 4017 | 0.122 | 0.0164 | Yes | ||
| 30 | FRS2 | 4219 | 0.114 | 0.0136 | Yes | ||
| 31 | RPS6KA6 | 4400 | 0.108 | 0.0119 | Yes | ||
| 32 | TP73 | 4512 | 0.104 | 0.0139 | Yes | ||
| 33 | NTF3 | 4626 | 0.100 | 0.0158 | Yes | ||
| 34 | SORT1 | 4766 | 0.095 | 0.0162 | Yes | ||
| 35 | MAP3K1 | 4779 | 0.095 | 0.0236 | Yes | ||
| 36 | PIK3CB | 4965 | 0.090 | 0.0216 | Yes | ||
| 37 | MAPK1 | 5144 | 0.085 | 0.0200 | Yes | ||
| 38 | NTRK1 | 5272 | 0.081 | 0.0211 | Yes | ||
| 39 | MAPK10 | 5273 | 0.081 | 0.0291 | Yes | ||
| 40 | MAPK8 | 5274 | 0.081 | 0.0371 | Yes | ||
| 41 | ZNF274 | 5376 | 0.078 | 0.0397 | Yes | ||
| 42 | AKT1 | 5405 | 0.078 | 0.0461 | Yes | ||
| 43 | SH2B1 | 5686 | 0.070 | 0.0390 | Yes | ||
| 44 | YWHAE | 5777 | 0.068 | 0.0422 | Yes | ||
| 45 | MAP2K5 | 5781 | 0.068 | 0.0500 | Yes | ||
| 46 | SH2B3 | 5888 | 0.065 | 0.0523 | Yes | ||
| 47 | RHOA | 5889 | 0.065 | 0.0603 | Yes | ||
| 48 | PDK1 | 6361 | 0.054 | 0.0428 | Yes | ||
| 49 | PRDM4 | 6546 | 0.049 | 0.0409 | Yes | ||
| 50 | YWHAG | 6629 | 0.048 | 0.0444 | Yes | ||
| 51 | MAGED1 | 6954 | 0.041 | 0.0349 | Yes | ||
| 52 | KRAS | 6957 | 0.041 | 0.0428 | Yes | ||
| 53 | CALM3 | 7021 | 0.039 | 0.0474 | Yes | ||
| 54 | CAMK2A | 7397 | 0.031 | 0.0352 | Yes | ||
| 55 | PSEN1 | 7445 | 0.030 | 0.0406 | Yes | ||
| 56 | RAF1 | 7492 | 0.029 | 0.0461 | Yes | ||
| 57 | CALML6 | 7588 | 0.027 | 0.0490 | Yes | ||
| 58 | YWHAB | 7590 | 0.027 | 0.0569 | Yes | ||
| 59 | AKT2 | 7783 | 0.023 | 0.0546 | Yes | ||
| 60 | MAPK3 | 7950 | 0.020 | 0.0536 | Yes | ||
| 61 | RAP1A | 8006 | 0.019 | 0.0586 | Yes | ||
| 62 | SHC2 | 8150 | 0.016 | 0.0589 | Yes | ||
| 63 | SOS1 | 8185 | 0.016 | 0.0651 | Yes | ||
| 64 | RIPK2 | 8312 | 0.013 | 0.0663 | Yes | ||
| 65 | ABL1 | 8493 | 0.009 | 0.0645 | Yes | ||
| 66 | PLCG1 | 8728 | 0.004 | 0.0599 | Yes | ||
| 67 | CAMK2B | 8900 | 0.001 | 0.0586 | Yes | ||
| 68 | MAP3K5 | 8961 | -0.000 | 0.0634 | Yes | ||
| 69 | RAC1 | 9060 | -0.002 | 0.0661 | Yes | ||
| 70 | CALM1 | 9305 | -0.007 | 0.0609 | Yes | ||
| 71 | RPS6KA3 | 9328 | -0.008 | 0.0677 | Yes | ||
| 72 | CAMK2G | 9447 | -0.010 | 0.0694 | Yes | ||
| 73 | YWHAH | 9617 | -0.013 | 0.0682 | Yes | ||
| 74 | MAPK9 | 9679 | -0.015 | 0.0729 | Yes | ||
| 75 | NFKB1 | 9728 | -0.016 | 0.0783 | Yes | ||
| 76 | MAPK14 | 9949 | -0.020 | 0.0744 | Yes | ||
| 77 | HRAS | 10032 | -0.021 | 0.0780 | Yes | ||
| 78 | NGFRAP1 | 10257 | -0.025 | 0.0739 | Yes | ||
| 79 | CALM2 | 10416 | -0.028 | 0.0734 | Yes | ||
| 80 | CRKL | 10644 | -0.033 | 0.0691 | Yes | ||
| 81 | IKBKB | 10665 | -0.033 | 0.0760 | Yes | ||
| 82 | YWHAZ | 10718 | -0.034 | 0.0812 | Yes | ||
| 83 | RELA | 10805 | -0.036 | 0.0846 | Yes | ||
| 84 | MAPK7 | 10963 | -0.041 | 0.0841 | Yes | ||
| 85 | NRAS | 11153 | -0.045 | 0.0819 | Yes | ||
| 86 | RPS6KA5 | 11641 | -0.056 | 0.0636 | Yes | ||
| 87 | SHC3 | 11648 | -0.057 | 0.0712 | Yes | ||
| 88 | JUN | 11703 | -0.058 | 0.0763 | Yes | ||
| 89 | MAP2K2 | 12201 | -0.070 | 0.0575 | Yes | ||
| 90 | RAP1B | 12330 | -0.073 | 0.0585 | Yes | ||
| 91 | RAPGEF1 | 12367 | -0.074 | 0.0646 | Yes | ||
| 92 | NGFR | 12465 | -0.076 | 0.0674 | Yes | ||
| 93 | PIK3R5 | 12488 | -0.077 | 0.0742 | Yes | ||
| 94 | CDC42 | 12574 | -0.080 | 0.0776 | Yes | ||
| 95 | ARHGDIA | 12785 | -0.086 | 0.0742 | Yes | ||
| 96 | NGF | 13059 | -0.094 | 0.0675 | Yes | ||
| 97 | NFKBIB | 13217 | -0.099 | 0.0670 | Yes | ||
| 98 | MAPKAPK2 | 13264 | -0.101 | 0.0725 | Yes | ||
| 99 | SHC1 | 13433 | -0.106 | 0.0714 | Yes | ||
| 100 | NTRK3 | 13453 | -0.106 | 0.0784 | Yes | ||
| 101 | MAP2K7 | 13571 | -0.110 | 0.0801 | Yes | ||
| 102 | GRB2 | 13603 | -0.112 | 0.0864 | Yes | ||
| 103 | MAPK12 | 13645 | -0.113 | 0.0922 | Yes | ||
| 104 | IRAK4 | 13818 | -0.120 | 0.0909 | Yes | ||
| 105 | MAP2K1 | 14041 | -0.131 | 0.0869 | Yes | ||
| 106 | ATF4 | 14093 | -0.133 | 0.0921 | Yes | ||
| 107 | MAPK13 | 14159 | -0.136 | 0.0966 | Yes | ||
| 108 | PLCG2 | 14313 | -0.145 | 0.0964 | Yes | ||
| 109 | IRAK2 | 14533 | -0.155 | 0.0925 | Yes | ||
| 110 | BAX | 14600 | -0.158 | 0.0970 | Yes | ||
| 111 | ARHGDIB | 14760 | -0.168 | 0.0964 | Yes | ||
| 112 | RPS6KA4 | 14855 | -0.175 | 0.0993 | Yes | ||
| 113 | NFKBIE | 14967 | -0.183 | 0.1013 | Yes | ||
| 114 | PRKCD | 14978 | -0.183 | 0.1087 | Yes | ||
| 115 | BAD | 15014 | -0.187 | 0.1149 | Yes | ||
| 116 | TP53 | 15141 | -0.196 | 0.1160 | Yes | ||
| 117 | PIK3CD | 15256 | -0.205 | 0.1179 | Yes | ||
| 118 | CSK | 15348 | -0.213 | 0.1210 | Yes | ||
| 119 | NTRK2 | 15546 | -0.232 | 0.1183 | Yes | ||
| 120 | IRAK1 | 15778 | -0.260 | 0.1138 | Yes | ||
| 121 | RPS6KA1 | 15789 | -0.261 | 0.1213 | Yes | ||
| 122 | MAPK11 | 15850 | -0.269 | 0.1261 | Yes | ||
| 123 | PIK3R2 | 16205 | -0.318 | 0.1149 | No | ||
| 124 | SH2B2 | 16682 | -0.421 | 0.0972 | No | ||
| 125 | NTF4 | 17538 | -0.757 | 0.0590 | No |
